We had a customer in the past week that totally clogged up our Astaro Security appliance (that was protected against DoS by disallowing more than 20 concurrent connections to the SMTP server). Further study taught us that they receive 20000 spam emails per day on average.
Fake MX is a good practice, but we also sped up our deployment of our new spamfilter using Maia Mailguard. This baby had no trouble intercepting all spam messages. It's based on amavisd-new, Postfix and of course ClamAV. Cool stuff.
Maia Mailguard - Trac
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